Dr. William J. Crumb Jr., Ph.D. Founder and Scientific Director
Dr. Crumb, the leading expert on cardiac ion channel physiology and pharmacology, established Zenas Technologies in 1996. A pioneer in his field, Dr. Crumb translated his expertise in cardiovascular pharmacology and research into defining the ion channel mechanisms underlying drugs with adverse cardiac effects and characterizing the relationship between hERG block and QT prolongation.

Dr. Crumb continues to develop innovative methodologies using native human cardiac myocytes and conducting studies at physiologic temperatures. He is also translating his cardiovascular expertise into central nervous system screening and analyzing the neuronal sodium channel for efficacy.

To date, he has given numerous presentations, published more than 35 papers and provided reviews for the top industry journals defining the mechanisms and associated risk factors for QT prolongation and
investigation of non-hERG currents in cardiac safety.

Before devoting his time to Zenas Technologies, Dr. Crumb was an Adjunct Assistant Professor at the Department of Pediatrics, Division of Cardiology at the Tulane University School of Medicine and the Director of Pediatric Clinical Research.

Dr. Crumb received his B.A. Degree in Psychology from the University of New Orleans (1987) and Ph.D. in Pharmacology from Tulane University in 1991.
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